Reproducible compute & telemetry for
genomics, supercomputing & earth science.
Orchestrate multi-petabyte instrumentation data, automate HPC cluster node governance, and guarantee immutable provenance for experimental discoveries.
Orchestrating multi-terabyte genomic variant calling with deterministic reproducibility
High-Throughput Sequencing & Bioinformatics Pipelines
Next-generation sequencing core facilities generate hundreds of terabytes of raw BCL and FASTQ reads weekly. Colibri automates data movement from sequencers to HPC clusters, manages storage tiering, and enforces pipeline provenance.
Manual script glue, sequencer IO bottlenecks, and unindexed petabyte storage cause run backlogs and untracked pipeline versions.
Colibri triggers automated Nextflow and Snakemake pipelines the moment sequencer chemistry completes, verifies raw checksums, and auto-tiers files to cost-effective cold storage.
Core Capabilities & Pipeline Standards
Instrumentation Workflow & Compute Pipeline
Detect run completion on Illumina NovaSeq / Nanopore PromethION systems.
Auto-submit alignment and variant-calling jobs to SLURM or Kubernetes GPU nodes.
Evaluate Q30 scores, read depth coverage, and contamination metrics in real time.
Anchor pipeline execution graph and Git commit hashes for publication reproducibility.
Deterministic data lineage from raw sensor photons to published paper.
DAG Provenance Tracking
Every transformation graph records exact software container image digests (SHA-256), environment variable flags, and CPU architecture parameters.
Automated Cold Tiering
Move petabytes of raw uncompressed detector frames to low-cost archival storage while keeping metadata and index pointers instantly searchable.
Inter-Institute Sharing
Securely federate multi-center research data with tokenized scoped access, allowing international consortia to collaborate without copying petabytes.
Research Infrastructure Questions
Can Colibri integrate with our on-premises SLURM cluster and Lustre filesystem?
Yes. Colibri runs lightweight POSIX daemon agents that communicate with SLURM REST APIs, Lustre changelogs, and GPFS filesystems without kernel modifications.
How does Colibri support grant-funded grant compliance (NIH, NSF, Horizon)?
Colibri automatically generates data management plan (DMP) execution reports, tracking data sharing, storage expenditures, and compute allocation utilization.
Can we run our own workflow managers (Nextflow, Snakemake, Cromwell)?
Yes. Colibri acts as the overarching orchestration and telematics layer, triggering and monitoring your existing workflow engines via event triggers.
Accelerate your scientific discoveries with Colibri.
Connect your lab sequencers, supercomputers, and observational sensors to Colibri today.